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What is the main cause of overactive bladder? Within the body, OAB is often the result of spasms in the detrusor muscle, the main muscle of the urinary bladder wall. When the brain senses the bladder is about half full, it usually sends out nerve signals. These cause the pelvic floor and sphincter muscles to relax while the detrusor contracts, squeezing out urine.
What drug is used as an antispasmodic to treat overactive bladder? These medications include: oxybutynin (Ditropan XL, Oxytrol) tolterodine (Detrol, Detrol LA) trospium (Sanctura)
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Can you have pain with an overactive bladder? Conclusions. Overactive bladder and IC can present with similar symptoms, such as urinary urgency, frequency, and nocturia. Urge urinary incontinence is a common feature of OAB, whereas pelvic pain is typically associated with IC.


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